Monobutyrin Animal Feed Additive CAS NO.60-01-5

Monobutyrin(Glycerol Monobutyrate or GMB),as an kind of derivative of butyrate,it is synthesized by esterification of butyric acid and glycerol. It is fully soluble in water,odorless and passing through stomach in the form of glycerides.During animals production,it behaves as hematopoiesis bacteriostasis,promotion of intestinal development and oil emulsification,enhancing the digestion and absorption of animal nutrients,improving the growth performance and health etc.

Product Parameters

Name: Monobutyrin((also name as Glycerol Monobutyrate or GMB))

CAS RN: 557-25-5

Formular: C7H14O4

FW: 162.18

Boiling Pt：208.462℃

Content：≥50% or 60% for optipn

Features

♦ Combined in covalent bond,butyric acid and glycerol are stable at PH1-7 and 230℃.

♦ Naturally passing through stomach. Directly absorbed by intestinal epithelial cell.

♦ Good water solubility,convenient addition in drinking water.

♦ PH independent,working throughout the digestive tract.

Functional Mechanisms

Hematopoiesis

Promote angiogenesis

Monobutyrin is the key regulatory factor of angiogenesis during normal tissue and cell development.(reported in the international heavyweight

journal "Cell" in 2014), it plays an important role in the growth and development of tissues and repair after injury. After being directly absorbed

by intestinal epithelium, glycerol monobutyrate will improve the intestinal villi microvascular damage caused by weaning stress, promote the growth

of villi and the intestinal health of piglets by means of regulating the formation of intestinal microvascular.

Promote hemoglobin synthesis

Butyric acid promotes hemoglobin synthesis, increases the number of red blood cells in the blood, and enhances active oxygen carrying capacity,

thereby strengthening endogenous life support systems. Sufficient blood and Qi leads to vigorous spirit, it is shown as red fur ,increasing survival

rate and evenness on animals.

Emulsification

Glycerol monobutyrate is a non-ionic surfactant with lipophilic alkyl group and hydrophilic hydroxyl group, which can be used as w/o emulsifier or

o/w emulsifier with good emulsification stability.It can emulsify lipids (fatty acids, fat soluble products, such as pigments and fat soluble vitamins)

with bile salts , and promote the digestion and absorption of lipids by animals, especially young livestock and poultry, so as to improve the utilization

rate of lipids.

Bacteriostasis

Monobutyrin has molecular polarity, which can effectively penetrate the hydrophilic cell membrane of some major pathogens, invade bacterial

cells, and then kill harmful bacteria. It can effectively inhibit the propagation of Escherichia coli, Vibrio, Aeromonas, Salmonella, Staphylococcus

aureus, Clostridium perfringens and other harmful bacteria. For the pathogenic bacteria , which mainly colonized in the hindgut and cecum (such

as Salmonella and Clostridium perfringens)，the antibacterial effect was significantly better than sodium butyrate.